Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18301609 | 0.76 | AKR1B1 (0.52) | P2RX7SMN1; SMN2KMT2ACYP3A4CD38 | |
| SCHEMBL8485672 | 0.75 | AKR1B1 (0.55) | SMN1; SMN2KMT2AMEN1CYP3A4LMNA | |
| SCHEMBL13571671 | 0.72 | L3MBTL1 (0.44) | KMT2AKDM4ELMNAL3MBTL1TDP1 | |
| SCHEMBL4102194 | 0.69 | LMNA (0.59) | SMN1; SMN2KMT2AMEN1CYP3A4LMNA | |
| SCHEMBL6072587 | 0.68 | TAAR1 (0.41) | P2RX7SMN1; SMN2KMT2AMEN1CYP3A4 | |
| SCHEMBL1457038 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMEN1CD38KDM4E | |
| SCHEMBL7880397 | 0.68 | KDM4E (0.48) | P2RX7SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL23374527 | 0.66 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL12095676 | 0.66 | MMP13 (0.42) | KMT2AMEN1CYP3A4LMNAMAPT | |
| SCHEMBL16964041 | 0.66 | KMT2A (0.47) | SMN1; SMN2KMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272303-A | Pyrimido five-membered nitrogen heterocyclic derivative, preparation method and application thereof in medicine | 上海拓界生物医药科技有限公司 | 2021-08-17 | — | — | CN | disclosed |