Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626254 | 0.78 | HTT (0.38) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| SCHEMBL3743731 | 0.77 | AKR1B1 (0.59) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| SCHEMBL28634747 | 0.75 | P2RX7 (0.38) | KMT2AMEN1LMNACYP3A4MAPT | |
| SCHEMBL13739934 | 0.75 | KMT2A (0.65) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| SCHEMBL1429298 | 0.74 | AKR1B1 (0.55) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| SCHEMBL1395814 | 0.74 | AKR1B1 (0.65) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| Ammonia Solution, Strong SCHEMBL27532390 | 0.73 | AKR1B1 (0.53) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| Hydrochloric Acid SCHEMBL5297667 | 0.72 | ADRA2A (0.65) | AKR1B1KMT2AMEN1ADRA2AMAPK1 | |
| SCHEMBL4102194 | 0.72 | LMNA (0.59) | KMT2AMEN1LMNACYP3A4CYP2D6 | |
| SCHEMBL2525484 | 0.71 | AKR1B1 (0.68) | AKR1B1KMT2AMEN1ADRA2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962492-A | ANTIASTHMA AGENTS; ANTIINFLAMMATORY AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |