Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646753 | 0.83 | NISCH (0.43) | HSD11B1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1275106 | 0.74 | MAPT (0.42) | EGLN2AHRHSD11B1GRM5MAPT | |
| SCHEMBL22261807 | 0.73 | CCNB2 (0.37) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29624840 | 0.68 | AHR (0.64) | AHRHSD11B1MAPTALDH1A1RAB9A | |
| SCHEMBL464507 | 0.68 | AHR (0.64) | AHRHSD11B1MAPTALDH1A1RAB9A | |
| SCHEMBL28630972 | 0.68 | LMNA (0.36) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3453300 | 0.67 | GRM5 (0.51) | EGLN2AHRHSD11B1GRM5MAPT | |
| SCHEMBL3631532 | 0.67 | RAB9A (0.50) | EGLN2AHRHSD11B1MAPTMEN1 | |
| SCHEMBL28635232 | 0.66 | HSP90AB1 (0.35) | GRM5HSP90AB1 | |
| SCHEMBL28632034 | 0.66 | GRM2 (0.35) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026050-B | Novel compounds as ROR gamma modulators | 格兰马克药品股份有限公司 | 2021-04-30 | — | — | CN | disclosed |