Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635736 | 0.80 | TSHR (0.47) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL9808496 | 0.78 | TSHR (0.46) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL27698103 | 0.78 | TSHR (0.56) | KMT2AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL787248 | 0.77 | TSHR (0.44) | ALDH1A1KDM4ETSHRLMNAHSD17B10 | |
| SCHEMBL27948846 | 0.76 | TSHR (0.47) | KMT2AALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL28023655 | 0.76 | TSHR (0.50) | KMT2AALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL5872395 | 0.73 | LMNA (0.45) | KMT2AALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL3182768 | 0.73 | LMNA (0.42) | GAAALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL20408695 | 0.73 | GAA (0.56) | GAAKMT2AALDH1A1LMNA | |
| SCHEMBL27671277 | 0.71 | ATM (0.44) | GAAALDH1A1TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |