Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631330 | 0.85 | BRAF (0.56) | BRAFBRD4PIK3CALMNAALDH1A1 | |
| SCHEMBL28924972 | 0.80 | PIK3CA (0.60) | BRAFBRD4PIK3CAMETAP2PIK3CD | |
| SCHEMBL28961950 | 0.80 | BRAF (0.61) | BRAFBRD4PIK3CAMAPTMEN1 | |
| SCHEMBL2880810 | 0.75 | METAP2 (0.47) | BRAFBRD4PIK3CAMAPTMEN1 | |
| SCHEMBL561243 | 0.74 | PIK3CA (0.71) | BRAFBRD4PIK3CAMAPTMEN1 | |
| SCHEMBL2879628 | 0.72 | BRD4 (0.50) | BRAFBRD4PIK3CAMAPTMEN1 | |
| SCHEMBL28631160 | 0.71 | BRAF (0.55) | BRAFBRD4PIK3CAMAPK1METAP2 | |
| SCHEMBL3433766 | 0.70 | METAP2 (0.51) | BRAFBRD4PIK3CAMAPTMEN1 | |
| SCHEMBL2194146 | 0.70 | PIK3CA (0.69) | BRD4PIK3CAMETAP2PIK3CDPIK3CB | |
| SCHEMBL22886577 | 0.70 | BRAF (0.57) | BRAFBRD4PIK3CAMETAP2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659765-B | Use of dianhydrogalactitol and analogs or derivatives thereof for treating non-small cell lung cancer and ovarian cancer | 德玛医药 | 2021-08-13 | — | — | CN | disclosed |