SCHEMBL20522283

SCHEMBL20522283

CCCOc1ccc(-c2ccccc2N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.49
NPC1 O15118 5/20 0.49
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HSD17B10 Q99714 3/20 0.48
CYP1A2 P05177 4/20 0.48
GAA P10253 2/20 0.48
TP53 P04637 1/20 0.48
CYP2C19 P33261 3/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2D6 P10635 1/20 0.45
CYP19A1 P11511 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396847 0.86 TDP1 (0.53) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL28804469 0.79 RAB9A (0.53) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL9153925 0.77 CHRNB2 (0.62) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL25620593 0.77 CHRNB2 (0.62) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL2056312 0.77 CHRNB2 (0.62) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL28636259 0.77 CHRNB4 (0.70) ALDH1A1KDM4ESMN1; SMN2MAPTCYP1A2
SCHEMBL6836988 0.77 CYP3A4 (0.63) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL17108413 0.77 CYP3A4 (0.63) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL9152649 0.77 CYP3A4 (0.63) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL27670043 0.77 LTA4H (0.63) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 RAB9A 838/4885NPC1 3535/4885ALDH1A1 1183/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT RAB9A 3346/4885NPC1 4774/4885ALDH1A1 1681/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS RAB9A 3332/4885NPC1 4800/4885ALDH1A1 1490/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 RAB9A 1349/4885NPC1 4752/4885ALDH1A1 1415/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT RAB9A 3514/4885NPC1 4709/4885ALDH1A1 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.