Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292471 | 0.73 | TP53 (0.67) | POLBMAPTTP53GAAMAPK1 | |
| SCHEMBL5929645 | 0.65 | FABP3 (0.47) | PPARAMEN1KMT2ACSNK2A1FABP3 | |
| SCHEMBL3061423 | 0.65 | DHODH (0.50) | KMT2AFABP3FABP4FABP5TP53 | |
| SCHEMBL4433976 | 0.65 | CSF1R (0.48) | MAPTCSNK2A1FABP3FABP4FABP5 | |
| SCHEMBL3066041 | 0.63 | DHODH (0.47) | KMT2AFABP3FABP4FABP5 | |
| SCHEMBL28204900 | 0.62 | FABP4 (0.46) | MEN1KMT2AFABP3FABP4FABP5 | |
| SCHEMBL20138876 | 0.62 | PDE10A (0.40) | MEN1KMT2AMAPTFABP3FABP4 | |
| SCHEMBL1841268 | 0.62 | P2RX3 (0.43) | MAPT | |
| SCHEMBL20138862 | 0.61 | FABP4 (0.44) | KMT2AFABP3FABP4FABP5GAA | |
| SCHEMBL17060022 | 0.60 | CYP3A4 (0.60) | MEN1KMT2APOLBRAD52GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109730996-B | Quinoline structure type androgen receptor antagonist and application thereof | 浙江大学 | 2021-08-24 | — | — | CN | disclosed |