Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL558316 | 0.91 | CYP1A2 (0.81) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL10627914 | 0.86 | CYP1A2 (0.90) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL3416 | 0.86 | CYP1A2 (1.00) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL10486461 | 0.86 | CYP1A2 (1.00) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL273260 | 0.86 | CYP1A2 (1.00) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL29767730 | 0.86 | CYP1A2 (1.00) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL5336584 | 0.84 | CYP1A2 (0.85) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL27341486 | 0.84 | CYP1A2 (0.85) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL7207908 | 0.84 | CYP1A2 (0.94) | CYP1A2POLBPTPN22IDO1PLAU | |
| 1-Naphthol SCHEMBL11319254 | 0.84 | CYP1A2 (0.94) | CYP1A2POLBPTPN22IDO1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461553-A | Synthesis method of dapoxetine and dapoxetine hydrochloride | 上海科利生物医药有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113461553-A | Synthesis method of dapoxetine and dapoxetine hydrochloride | 上海科利生物医药有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-113461553-A | Synthesis method of dapoxetine and dapoxetine hydrochloride | 上海科利生物医药有限公司 | 2021-10-01 | — | — | CN | disclosed |