SCHEMBL28638828

SCHEMBL28638828

CSC(=N)NCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
IDO1 P14902 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
EPHX2 P34913 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
MAPT P10636 2/20 0.47
RORC P51449 2/20 0.47
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772893 0.89 IDO1 (0.61) ALDH1A1IDO1KMT2AMEN1MAPT
Iodide SCHEMBL10592683 0.87 IDO1 (0.59) ALDH1A1IDO1KMT2AMEN1MAPT
SCHEMBL15462253 0.80 MAPT (0.53) ALDH1A1LMNAIDO1KMT2AMEN1
SCHEMBL7785365 0.79 TPSAB1 (0.52) IDO1MAPTCYP1A2CYP2D6
SCHEMBL28272776 0.79 LMNA (0.54) ALDH1A1LMNAKMT2ARAB9ANPC1
Iodide SCHEMBL11389787 0.77 MEN1 (0.52) ALDH1A1KMT2AMEN1RAB9ANPC1
SCHEMBL27378749 0.77 CA2 (0.41) LMNAIDO1MAPTNPC1CA1
SCHEMBL17198935 0.77 ALDH1A1 (0.54) ALDH1A1LMNAKMT2AMEN1EPHX2
SCHEMBL8279987 0.76 ALDH1A1 (0.59) ALDH1A1LMNAIDO1KMT2AMEN1
Hydrochloric Acid SCHEMBL28486835 0.75 ALDH1A1 (0.53) ALDH1A1LMNAKMT2AMEN1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107056636-B Oseltamivir derivative and preparation method and application thereof 山东大学 2021-05-11 CN disclosed