Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10592683 | 0.98 | IDO1 (0.59) | IDO1ALOX12HPGDALDH1A1MAPT | |
| SCHEMBL28638828 | 0.89 | ALDH1A1 (0.50) | IDO1ALOX12ALDH1A1MAPTNPC1 | |
| SCHEMBL15462253 | 0.82 | MAPT (0.53) | IDO1HPGDALDH1A1MAPTNPC1 | |
| SCHEMBL7785365 | 0.81 | TPSAB1 (0.52) | IDO1MAPT | |
| SCHEMBL4646862 | 0.81 | IDO1 (0.49) | IDO1ALOX12HPGDALDH1A1MAPT | |
| Bromide SCHEMBL11806748 | 0.79 | IDO1 (0.47) | IDO1ALOX12HPGDALDH1A1MAPT | |
| Iodide SCHEMBL11389787 | 0.79 | MEN1 (0.52) | ALOX12HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7787881 | 0.79 | LOXL2 (0.45) | IDO1ALOX12ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8279987 | 0.78 | ALDH1A1 (0.59) | IDO1HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL13120816 | 0.77 | ALOX12 (0.56) | IDO1ALOX12HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702547-B | Transmembrane polypeptides obtained by modification of amino acid side chains | 深圳湾实验室坪山生物医药研发转化中心 | 2023-11-07 | — | — | CN | claimed |
| CN-1190416-C | Substituted phenyl alkyl nitrogen monoxide synthase inhibitor and its prepn and use | UNIV CHINA PHARMACY (CN) | 2005-02-23 | — | — | CN | disclosed |
| CN-1388118-A | Substituted phenyl alkyl nitrogen monoxide synthase inhibitor and its prepn and use | UNIV CHINA PHARMACY (CN) | 2003-01-01 | — | — | CN | disclosed |
| CN-1057520-C | N,N'-substituted imidodicarbonimidic diamides derived from hydroxylamines | JACOBUS PHARMA CO INC (US) | 2000-10-18 | — | — | CN | disclosed |
| EP-0625967-B1 | N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES | JACOBUS PHARMA CO INC (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1995028377-A1 | GUANIDINE COMPOUNDS AS REGULATORS OF NITRIC OXIDE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-10-26 | — | — | WO | disclosed |
| EP-0625967-A1 | N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES. | JACOBUS PHARMA CO INC (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5322858-A | Antimicrobial, antiparasitic agents | JACOBUS PHARMACEUTICAL CO. INC. (US) | 1994-06-21 | — | — | US | disclosed |
| CN-1076689-A | From oxyamine deutero-N, N '-'-substituted imidodicarbonimidic diamides | JACOBUS PHARMA CO INC (US) | 1993-09-29 | — | — | CN | disclosed |
| WO-1993016037-A1 | N,N'-SUBSTITUTED IMIDOCARBONIMIDIC DIAMIDES DERIVED FROM HYDROXYLAMINES | JACOBUS PHARMACEUTICAL CO., INC. (US) | 1993-08-19 | — | — | WO | disclosed |