SCHEMBL28638865

SCHEMBL28638865

C=Cc1ccccc1C(=O)NOC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.42
CTSD P07339 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CFTR P13569 1/20 0.41
HSD17B10 Q99714 1/20 0.41
EGFR P00533 1/20 0.38
TSHR P16473 3/20 0.38
LMNA P02545 2/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
KMT2A Q03164 1/20 0.37
LIG1 P18858 1/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
ATM Q13315 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61520 0.80 TSHR (0.55) ALDH1A1CFTRHSD17B10TSHRLMNA
SCHEMBL5477577 0.80 CTSD (0.49) CTSDALDH1A1HSD17B10TSHRCA1
SCHEMBL4903302 0.80 GAA (0.53) ALDH1A1POLB
Ethane SCHEMBL28020377 0.79 GAA (0.50) ALDH1A1HSD17B10LMNACA1CA9
SCHEMBL17255814 0.78 GAA (0.53) ALDH1A1HSD17B10LMNACA1CA9
Methoxymethane SCHEMBL6152425 0.77 ALDH1A1 (0.48) PTGS2ALDH1A1HSD17B10TSHRLMNA
SCHEMBL7222038 0.77 PTGS2 (0.44) PTGS2CTSDALDH1A1CFTRHSD17B10
SCHEMBL4258990 0.76 SLC6A3 (0.51) ALDH1A1CFTRHSD17B10TSHRLMNA
SCHEMBL1740295 0.76 MAPT (0.40) CTSDALDH1A1CFTRHSD17B10TSHR
Acrylic Acid SCHEMBL28669848 0.75 TSHR (0.49) ALDH1A1CFTRHSD17B10TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113584507-B Method for continuously and electrically synthesizing sulfonylated isoindolinone by utilizing microreaction device 南京先进生物材料与过程装备研究院有限公司 2024-03-26 CN claimed
CN-113549939-B Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2022-10-28 CN claimed
CN-113584507-A Method for continuously and electrically synthesizing sulfonylated isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-11-02 CN claimed
CN-113549939-A Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-10-26 CN claimed
CN-113584507-B Method for continuously and electrically synthesizing sulfonylated isoindolinone by utilizing microreaction device 南京先进生物材料与过程装备研究院有限公司 2024-03-26 CN disclosed
CN-113584507-B Method for continuously and electrically synthesizing sulfonylated isoindolinone by utilizing microreaction device 南京先进生物材料与过程装备研究院有限公司 2024-03-26 CN disclosed
CN-113549939-B Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2022-10-28 CN disclosed
CN-113549939-B Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2022-10-28 CN disclosed
CN-113584507-A Method for continuously and electrically synthesizing sulfonylated isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-11-02 CN disclosed
CN-113584507-A Method for continuously and electrically synthesizing sulfonylated isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-11-02 CN disclosed
CN-113549939-A Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-10-26 CN disclosed
CN-113549939-A Method for continuously electrically synthesizing isoindolinone by using micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2021-10-26 CN disclosed