SCHEMBL547713

SCHEMBL547713

Brc1ccccc1Sc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
SIRT1 Q96EB6 1/20 0.45
MAPT P10636 3/20 0.44
KDM4E B2RXH2 1/20 0.44
NSD2 O96028 1/20 0.44
MAPK1 P28482 1/20 0.44
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473611 0.86 SMN1; SMN2 (0.53) LMNAMAPK1TDP1PDE7AHTR7
SCHEMBL9578982 0.84 MAPT (0.44) LMNASIRT1MAPTKDM4ENSD2
SCHEMBL29543575 0.84 LMNA (0.57) LMNAMAPTMAPK1TDP1PDE7A
SCHEMBL3282096 0.84 LMNA (0.57) LMNAMAPTMAPK1TDP1PDE7A
SCHEMBL3547807 0.82 SLC6A4 (0.50) LMNAHTR1AHTR3ACHRNA7PDE7A
SCHEMBL5685312 0.82 LMNA (0.41) LMNASIRT1MAPTKDM4ENSD2
SCHEMBL546680 0.82 CYP1A2 (0.46) LMNAMAPTMAPK1HTR1AHTR3A
SCHEMBL30968879 0.82 CYP1A2 (0.46) LMNAMAPTMAPK1HTR1AHTR3A
SCHEMBL795029 0.81 SIRT1 (0.54) LMNASIRT1MAPTKDM4ENSD2
SCHEMBL11817827 0.81 PNP (0.42) LMNAMAPTKDM4ENSD2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692093-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Solus Advanced Materials Co., Ltd. (KR) 2026-02-11 EP disclosed
CN-119462776-B N heteroatom-containing spirofluorene metal platinum complex and electroluminescent device thereof 西安欧得光电材料有限公司 2025-05-09 CN disclosed
CN-119462776-A N heteroatom-containing spirofluorene metal platinum complex and electroluminescent device thereof 西安欧得光电材料有限公司 2025-02-18 CN disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
CN-113130799-B Organic electronic element, display panel including the same, and display device including the same 乐金显示有限公司 2024-07-05 CN disclosed
CN-117964635-B Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-07-05 CN disclosed
US-20240190836-A1 XANTHENE DERIVATIVE COMPOUND HAVING HIGH REFRACTIVE INDEX AND (CO)POLYMER COMPRISING SAME Research & Business Foundation Sungkyunkwan University (KR) 2024-06-13 US disclosed
CN-117964635-A Organic luminescent material based on spiro thioxanthene and preparation method and application thereof 大连理工大学 2024-05-03 CN disclosed
US-20050014740-A1 Phenyl-piperazine derivatives as serotonin reuptake inhibitors H. LUNDBECK A/S (DK) 2005-01-20 US disclosed
WO-2004087156-A1 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS H. LUNDBECK A/S (DK) 2004-10-14 WO disclosed
WO-2004087662-A1 4-(2-PHENYLSULFANYL-PHENYL)-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS H. LUNDBECK A/S (DK) 2004-10-14 WO disclosed
EP-1458689-A1 ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES H. LUNDBECK A/S (DK) 2004-09-22 EP disclosed
EP-1436271-A1 PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS H. Lundbeck A/S (DK) 2004-07-14 EP disclosed
WO-2003053942-A1 ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES H. LUNDBECK A/S (DK) 2003-07-03 WO disclosed
WO-2003029232-A1 PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS H. LUNDBECK A/S (DK) 2003-04-10 WO disclosed
WO-1994026264-A1 (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE ABBOTT LABORATORIES (US) 1994-11-24 WO disclosed
US-5288848-A Reacting mono- and dihalogenated aromatics with alkali sulfide ; low corrosion during processing BAYER AKTIENGESELLSCHAFT (DE) 1994-02-22 US disclosed
US-4760127-A Reacting dihalogen aromatics and alkali metal sulfide in presence of a monohalogen compound and a monomercapto compound BAYER AG (DE) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014740-A1 Phenyl-piperazine derivatives as serotonin reuptake inhibitors TPH1, HTR5A, HTR2C LMNA 3978/4885SIRT1 1807/4885MAPT 1795/4885
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device TRMT1L, TLK1, TSPO LMNA 2454/4885SIRT1 4682/4885MAPT 134/4885
US-20240190836-A1 XANTHENE DERIVATIVE COMPOUND HAVING HIGH REFRACTIVE INDEX AND (CO)POLYMER COMPRISING SAME WEE1, SQLE, WASF2 LMNA 1327/4885SIRT1 163/4885MAPT 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.