Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637480 | 0.83 | ADRA1A (0.40) | ADRA1AKMT2AADRA1DADRA1BP2RX7 | |
| SCHEMBL2575919 | 0.81 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL2575921 | 0.81 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL11949260 | 0.81 | P2RX7 (0.49) | ADRA1AKMT2AP2RX7 | |
| SCHEMBL28627005 | 0.80 | ACE (0.39) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9542954 | 0.77 | ADRA1A (0.46) | ADRA1AKMT2AADRA1DADRA1BP2RX7 | |
| SCHEMBL9382993 | 0.77 | ADRA1A (0.46) | ADRA1AKMT2AADRA1DADRA1BP2RX7 | |
| SCHEMBL13331904 | 0.75 | ALDH1A1 (0.48) | ADRA1AKMT2AADRA1DADRA1BALDH1A1 | |
| SCHEMBL9150751 | 0.74 | ALDH1A1 (0.50) | ADRA1AKMT2AADRA1DADRA1BALDH1A1 | |
| SCHEMBL8615386 | 0.74 | ADRA1A (0.45) | ADRA1AKMT2AADRA1DADRA1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307758-B | P2X7 receptor targeting probe precursor labeled by medical radioactive isotope | 复旦大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113307758-A | P2X7 receptor targeting probe precursor labeled by medical radioactive isotope | 复旦大学 | 2021-08-27 | — | — | CN | disclosed |