Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657465 | 0.86 | RAPGEF4 (0.37) | RAPGEF4KLK7FABP4PIK3C3 | |
| SCHEMBL28639443 | 0.81 | CYP2C19 (0.33) | — | |
| SCHEMBL20443037 | 0.72 | — | — | |
| SCHEMBL28802486 | 0.72 | PIK3C3 (0.48) | RAPGEF4FABP4PIK3C3 | |
| SCHEMBL26720584 | 0.70 | L3MBTL1 (0.44) | RAPGEF4 | |
| SCHEMBL23403832 | 0.69 | RAPGEF4 (0.36) | RAPGEF4FABP4PIK3C3 | |
| SCHEMBL31465621 | 0.69 | RAPGEF4 (0.36) | RAPGEF4FABP4PIK3C3 | |
| SCHEMBL28852705 | 0.69 | FABP4 (0.45) | RAPGEF4KLK7FABP4 | |
| SCHEMBL14677903 | 0.68 | RAPGEF4 (0.33) | RAPGEF4KLK7PIK3C3 | |
| SCHEMBL14678605 | 0.68 | CYP3A4 (0.35) | RAPGEF4KLK7PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198941-B | Pyrrolopyridine N-oxide derivative and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-09-28 | — | — | CN | disclosed |