Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 8/20 | 0.42 |
| ▸ | TACR3 | P29371 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646250 | 0.86 | CRHBP (0.49) | CRHBPCRHR2SIRT1ERN1ALDH1A1 | |
| SCHEMBL28632790 | 0.81 | CRHBP (0.49) | CRHBPCRHR2ERN1ALDH1A1TDP1 | |
| SCHEMBL28641417 | 0.77 | CRHBP (0.53) | CRHBPCRHR2ERN1ALDH1A1TDP1 | |
| SCHEMBL28635053 | 0.77 | CRHBP (0.49) | CRHBPCRHR2ERN1ALDH1A1TDP1 | |
| SCHEMBL11292185 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL28580966 | 0.71 | GPR35 (0.50) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL29672058 | 0.70 | ERN1 (0.44) | SIRT1ERN1ALDH1A1MAPTMEN1 | |
| SCHEMBL28792533 | 0.70 | ERN1 (0.44) | SIRT1ERN1ALDH1A1MAPTMEN1 | |
| SCHEMBL5247063 | 0.70 | L3MBTL1 (0.40) | ALDH1A1TDP1MAPTGAANPSR1 | |
| SCHEMBL9315238 | 0.69 | MAPT (0.43) | SIRT1ERN1ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493433-B | Benzopyrone derivative capable of serving as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-113493433-A | Benzopyrone derivative capable of being used as GPR35 receptor agonist, preparation method and application thereof | 泰州医药城国科化物生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |