Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629615 | 0.84 | SLC6A3 (0.64) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL18825620 | 0.84 | BCAT2 (0.59) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL229441 | 0.84 | BCAT2 (0.63) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL3416936 | 0.82 | SLC6A3 (0.62) | SLC6A3BCAT2ALDH1A1ALOX15HTT | |
| SCHEMBL28640320 | 0.82 | SLC6A3 (0.64) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL29697585 | 0.82 | BCAT2 (0.47) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL29697586 | 0.82 | BCAT2 (0.47) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL9532086 | 0.82 | BCAT2 (0.55) | SLC6A3BCAT2SLC6A4ALDH1A1ALOX15 | |
| SCHEMBL1965782 | 0.81 | BCAT2 (0.71) | SLC6A3BCAT2ALDH1A1HTTMEN1 | |
| SCHEMBL20943639 | 0.81 | SLC6A3 (0.44) | SLC6A3ALDH1A1ALOX15KDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683172-B1 | 11,21-Bisphenyl-19-norpregnane derivatives | AKZO NOBEL NV (NL) | 1997-08-13 | — | — | EP | disclosed |
| US-5620966-A | ANTIGLUOCORTICOID ACTIVITY | AKZO NOBEL N.V. (NL) | 1997-04-15 | — | — | US | disclosed |
| EP-0683172-A1 | 11,21-Bisphenyl-19-norpregnane derivatives | Akzo Nobel N.V. (NL) | 1995-11-22 | — | — | EP | disclosed |