Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622914 | 0.75 | CES2 (0.52) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL28625455 | 0.75 | KDM4E (0.49) | NAMPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28630343 | 0.74 | GLA (0.58) | KDM4EALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL28640398 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28923423 | 0.74 | CNR1 (0.51) | CNR1ALDH1A1NPC1RAB9ATAAR1 | |
| SCHEMBL28631610 | 0.74 | NPC1 (0.48) | CNR1ALDH1A1NPC1RAB9ATAAR1 | |
| SCHEMBL16825194 | 0.72 | GRIN2B (0.57) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL31686065 | 0.72 | NPC1 (0.61) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL26646019 | 0.72 | NPC1 (0.61) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28625023 | 0.71 | CYP3A4 (0.47) | CNR1ALDH1A1POLBHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |