Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 4/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101034 | 0.74 | MAPT (0.33) | ALOX15KMT2AL3MBTL1NPC1HPGD | |
| SCHEMBL22057205 | 0.71 | RAB9A (0.41) | SCN4AKMT2ASCN9ANPC1RAB9A | |
| SCHEMBL12126287 | 0.69 | — | — | |
| SCHEMBL27714139 | 0.68 | MAPT (0.41) | ALOX15KMT2ANPC1HPGDRAB9A | |
| SCHEMBL22390874 | 0.68 | ALOX15 (0.39) | ALOX15KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL3604417 | 0.67 | — | — | |
| SCHEMBL31493084 | 0.67 | — | — | |
| SCHEMBL2428782 | 0.66 | GSK3B (0.47) | SCN4ASCN9ACREBBP | |
| SCHEMBL17489137 | 0.66 | ALOX15 (0.50) | ALOX15KMT2ATDP1KDM4ERAB9A | |
| SCHEMBL28640710 | 0.66 | NOS1 (0.40) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563404-A | Process for the preparation of cholic acid derivatives | 华东师范大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-113563405-A | Cholic acid derivatives and their use in lowering cholesterol | 华东师范大学 | 2021-10-29 | — | — | CN | disclosed |