Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435774 | 0.81 | PSIP1 (0.41) | HSD11B1PSIP1 | |
| SCHEMBL4524280 | 0.81 | CA2 (0.47) | HSD11B1PSIP1CA2L3MBTL1 | |
| SCHEMBL7863515 | 0.81 | HSD11B1 (0.33) | HSD11B1PSIP1L3MBTL1 | |
| SCHEMBL9572295 | 0.80 | HSD11B1 (0.35) | HSD11B1PSIP1CA2L3MBTL1 | |
| SCHEMBL160580 | 0.79 | PSIP1 (0.56) | HTR6HSD11B1PSIP1 | |
| SCHEMBL28129004 | 0.77 | LOX (0.40) | PSIP1CA2CA12CA1CA4 | |
| SCHEMBL28206252 | 0.77 | PSIP1 (0.34) | HTR6HSD11B1PSIP1L3MBTL1 | |
| SCHEMBL4365964 | 0.76 | CA2 (0.39) | HSD11B1PSIP1CA2LOXL2CA12 | |
| SCHEMBL8926410 | 0.76 | THRB (0.42) | PSIP1CA2CA12CA1CA9 | |
| SCHEMBL10606555 | 0.76 | THRB (0.42) | PSIP1CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365984-A | LOX inhibitors | 癌症研究协会皇家癌症医院 | 2021-09-07 | — | — | CN | disclosed |