Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160580 | 0.86 | PSIP1 (0.56) | PSIP1ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10606555 | 0.86 | THRB (0.42) | PSIP1CYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL8926410 | 0.86 | THRB (0.42) | PSIP1CYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL28245872 | 0.86 | THRB (0.42) | PSIP1CYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL7863515 | 0.81 | HSD11B1 (0.33) | PSIP1ALDH1A1HSD17B10HSD11B1TDP1 | |
| SCHEMBL28640869 | 0.81 | HTR6 (0.33) | PSIP1HSD11B1 | |
| SCHEMBL4524280 | 0.81 | CA2 (0.47) | PSIP1ALDH1A1MAPTHSD11B1 | |
| SCHEMBL28129004 | 0.81 | LOX (0.40) | PSIP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9572295 | 0.80 | HSD11B1 (0.35) | PSIP1MAPTHSD11B1CYP2D6 | |
| SCHEMBL28206252 | 0.77 | PSIP1 (0.34) | PSIP1ALDH1A1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |