Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604600 | 1.00 | HSP90AA1 (0.43) | HSP90AA1MAOBL3MBTL1KMT2AMEN1 | |
| SCHEMBL30604559 | 0.91 | KMT2A (0.48) | MAOBL3MBTL1KMT2ATSHRMAPT | |
| SCHEMBL28644854 | 0.91 | KMT2A (0.48) | MAOBL3MBTL1KMT2ATSHRMAPT | |
| SCHEMBL28639031 | 0.83 | KMT2A (0.57) | HSP90AA1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL28641200 | 0.82 | ALDH1A1 (0.37) | L3MBTL1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL30604594 | 0.82 | ALDH1A1 (0.37) | L3MBTL1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL28656587 | 0.82 | TSHR (0.51) | HSP90AA1KMT2AMEN1TSHRMAPT | |
| SCHEMBL28925170 | 0.81 | CASP3 (0.47) | HSP90AA1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL28645332 | 0.78 | LMNA (0.41) | HSP90AA1KMT2AMEN1TSHRMAPT | |
| SCHEMBL30604585 | 0.78 | MEN1 (0.47) | KMT2AMEN1TSHRMAPTPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493438-B | Tetrahydroisoquinoline compounds | 南京再明医药有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113493438-A | Tetrahydroisoquinoline compounds | 江苏先声药业有限公司 | 2021-10-12 | — | — | CN | disclosed |