Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.83 |
| ▸ | MAPT | P10636 | 7/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21081852 | 0.91 | MAPT (1.00) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL11521612 | 0.82 | POLB (0.58) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28627570 | 0.81 | ALDH1A1 (0.74) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28367385 | 0.80 | POLB (0.62) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28629704 | 0.78 | MAPT (0.69) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29110239 | 0.78 | POLB (0.60) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28641204 | 0.77 | MAPT (0.72) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL12001998 | 0.77 | L3MBTL1 (0.69) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL27895847 | 0.76 | MGAM (0.62) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL12002216 | 0.75 | L3MBTL1 (0.65) | LMNAMAPTSMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483474-B | Preparation method of 2-methylene-1, 3, 5-triaryl-1, 5-pentanedione | 上海应用技术大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-110483474-A | A kind of preparation method of 2- methylene -1,3,5- triaryl -1,5- pentanedione | SHANGHAI INST TECH | 2019-11-22 | — | — | CN | disclosed |