Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100657 | 0.83 | HTR1A (0.58) | L3MBTL1LMNASMN1; SMN2CES2CES1 | |
| SCHEMBL21081852 | 0.83 | MAPT (1.00) | MAPTL3MBTL1NPSR1ALDH1A1LMNA | |
| SCHEMBL11523072 | 0.82 | HTR1A (0.57) | L3MBTL1ALDH1A1LMNASMN1; SMN2CES2 | |
| SCHEMBL28627570 | 0.81 | ALDH1A1 (0.74) | MAPTL3MBTL1NPSR1ALDH1A1LMNA | |
| SCHEMBL28640944 | 0.78 | LMNA (0.83) | MAPTL3MBTL1NPSR1ALDH1A1LMNA | |
| SCHEMBL2886568 | 0.78 | L3MBTL1 (0.62) | L3MBTL1NPSR1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL2886563 | 0.78 | L3MBTL1 (0.62) | L3MBTL1NPSR1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL31326036 | 0.76 | KMT2A (0.70) | L3MBTL1CES2CES1HTR1AADRA2A | |
| SCHEMBL27685616 | 0.75 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1SMN1; SMN2HTR1AADRA2A | |
| SCHEMBL12158740 | 0.74 | L3MBTL1 (0.62) | L3MBTL1NPSR1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483474-B | Preparation method of 2-methylene-1, 3, 5-triaryl-1, 5-pentanedione | 上海应用技术大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-110483474-A | A kind of preparation method of 2- methylene -1,3,5- triaryl -1,5- pentanedione | SHANGHAI INST TECH | 2019-11-22 | — | — | CN | disclosed |