Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16036357 | 0.83 | L3MBTL1 (0.54) | ALDH1A1KMT2APTK2BKDM4ESMN1; SMN2 | |
| SCHEMBL5507668 | 0.83 | ALDH1A1 (0.71) | LMNAALDH1A1KMT2APTK2BMEN1 | |
| SCHEMBL5052356 | 0.82 | LMNA (0.53) | LMNAALDH1A1KMT2APTK2BMEN1 | |
| SCHEMBL5055118 | 0.81 | LMNA (0.59) | LMNAALDH1A1KMT2AMEN1HIF1A | |
| SCHEMBL16787529 | 0.81 | ALDH1A1 (0.53) | LMNAALDH1A1KMT2APTK2BMEN1 | |
| SCHEMBL2555648 | 0.80 | LMNA (0.70) | LMNAALDH1A1KMT2APTK2BMEN1 | |
| SCHEMBL30194507 | 0.79 | SGMS2 (0.59) | LMNAALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL2999130 | 0.79 | SGMS2 (0.59) | LMNAALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL15766880 | 0.78 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL614689 | 0.78 | KDM4E (0.68) | LMNAALDH1A1KMT2APTK2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527237-A | Method for preparing abemostat, intermediate and preparation method of intermediate | 上海工程技术大学 | 2021-10-22 | — | — | CN | claimed |
| CN-113527237-A | Method for preparing abemostat, intermediate and preparation method of intermediate | 上海工程技术大学 | 2021-10-22 | — | — | CN | disclosed |