Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646599 | 0.88 | RAB9A (0.52) | ALKBH1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL6534698 | 0.85 | CYP1A2 (0.62) | ALKBH1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL28658874 | 0.84 | ALKBH1 (0.50) | ALKBH1P4HTMLMNAARMAOB | |
| SCHEMBL8572314 | 0.84 | NPC1 (0.57) | ALKBH1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL9424295 | 0.83 | MAOB (0.53) | NPC1RAB9APDGFRBPDGFRAENPP3 | |
| SCHEMBL28652217 | 0.82 | F2 (0.50) | ALKBH1NPC1RAB9APDGFRBPDGFRA | |
| SCHEMBL10128671 | 0.81 | LMNA (0.60) | RAB9AENPP3ENPP1IKBKELMNA | |
| SCHEMBL7653456 | 0.80 | MAOB (0.69) | ALKBH1RAB9ALMNAARPOLB | |
| SCHEMBL2559067 | 0.80 | P4HTM (0.49) | ALKBH1PDGFRBPDGFRAP4HTMLMNA | |
| SCHEMBL7781588 | 0.80 | MAOB (0.54) | ALKBH1RAB9AP4HTMMAOBGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109251166-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-109251166-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-01-22 | — | — | CN | disclosed |