SCHEMBL523641

SCHEMBL523641

CCO[Si](OCC)(c1ccccc1)c1ccccc1.Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.31
TP53 P04637 1/20 0.30
PIN1 Q13526 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34937 0.89 LTA4H (0.37) LTA4HTP53PIN1MAPT
SCHEMBL28187676 0.87 LTA4H (0.35) LTA4HTP53PIN1MAPT
Phosphine SCHEMBL23931373 0.87 LTA4H (0.35) LTA4HTP53PIN1MAPT
SCHEMBL712057 0.87 ESR1 (0.37) LTA4HTP53PIN1MAPT
SCHEMBL9765878 0.84 LTA4H (0.31) LTA4HTP53
SCHEMBL28100760 0.82 LTA4H (0.32) LTA4HTP53PIN1MAPT
SCHEMBL6046631 0.82 TSHR (0.33) LTA4HTP53PIN1MAPT
SCHEMBL28133626 0.82 MAPT (0.34) LTA4HTP53PIN1MAPT
SCHEMBL295849 0.81 LTA4H (0.34) LTA4HTP53PIN1MAPT
Ether SCHEMBL28645485 0.81 LTA4H (0.34) LTA4HTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2405982-B1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING (US) 2013-12-18 EP disclosed
US-8293939-B2 Methods for removing vicinal diols from lactic acid fermentation broth DOW CORNING CORPORATION (US) 2012-10-23 US disclosed
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2012-02-02 US disclosed
EP-2405982-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH Dow Corning Corporation (US) 2012-01-18 EP disclosed
WO-2010104677-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2010-09-16 WO disclosed
US-20090030222-A1 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES WITH SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION 2009-01-29 US disclosed
EP-1979422-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS Dow Corning Corporation (US) 2008-10-15 EP disclosed
WO-2007084245-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION (US) 2007-07-26 WO disclosed
WO-2005034205-A2 SELF ASSEMBLING NANOPARTICLE-POLYMER HYBRIDS DOW CORNING CORPORATION (US) 2005-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH SORD, LDHA, LDHB LTA4H 661/4885TP53 707/4885PIN1 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.