Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | KDM5C | P41229 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134643 | 0.85 | KDM1A (0.47) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29134657 | 0.85 | KMT2A (0.46) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29134646 | 0.83 | KDM1A (0.51) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29163821 | 0.82 | KMO (0.51) | KDM4EKDM4CALDH1A1POLBNPC1 | |
| SCHEMBL581398 | 0.81 | KDM4E (0.71) | KAT6AKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL29163838 | 0.80 | SMYD2 (0.47) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Nitrous Acid SCHEMBL28651257 | 0.80 | KDM4C (0.63) | KAT6AKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL946431 | 0.79 | ASIC3 (0.55) | KAT6AKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL3718393 | 0.79 | KDM4E (0.68) | KAT6AKDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL30772302 | 0.79 | KDM4E (0.68) | KAT6AKDM4EKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113712964-B | Application of 9,10 dihydrophenanthrene compound in preparation of coronavirus 3CL protease inhibitor | 上海中医药大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113712964-A | Application of 9, 10-dihydrophenanthrene compound in preparation of coronavirus 3CL protease inhibitor | 上海中医药大学 | 2021-11-30 | — | — | CN | disclosed |
| CN-113582915-A | Synthesis method of 4-substituted pyridine compound | 河南师范大学 | 2021-11-02 | — | — | CN | disclosed |