Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10131893 | 0.88 | MAOB (0.45) | LMNAAKT2BRD4CHEK1BRD2 | |
| SCHEMBL2872995 | 0.86 | NPC1 (0.48) | LMNAHTTL3MBTL1KMT2ANPC1 | |
| SCHEMBL2872108 | 0.83 | MAOB (0.51) | LMNAAKT2BRD4CHEK1BRD2 | |
| SCHEMBL10835370 | 0.77 | KDM4E (0.44) | LMNACHEK1ADORA2AL3MBTL1KMT2A | |
| SCHEMBL12306078 | 0.75 | LMNA (0.47) | LMNAAKT2BRD4CHEK1BRD2 | |
| SCHEMBL11560947 | 0.74 | PDE4B (0.44) | LMNAAKT2BRD4CHEK1BRD2 | |
| SCHEMBL31504610 | 0.73 | L3MBTL1 (0.54) | LMNAAKT2BRD4CHEK1BRD2 | |
| SCHEMBL3018231 | 0.72 | KDM4E (0.43) | LMNAAKT2HTTADRA2AADORA2A | |
| SCHEMBL1787324 | 0.72 | KDM4E (0.48) | L3MBTL1KDM4EPKM | |
| SCHEMBL10015953 | 0.71 | MAOB (0.42) | LMNAAKT2BRD4CHEK1BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130359-A1 | Fungicidal Pyridazines, Processes for Their Preparation and Their Use for Controlling Harmful Fungi, and Compositions Comprising Them | BASF SE (DE) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130359-A1 | Fungicidal Pyridazines, Processes for Their Preparation and Their Use for Controlling Harmful Fungi, and Compositions Comprising Them | PNPO, CYP4Z1, CYP3A5 | LMNA 1488/4885AKT2 4403/4885BRD4 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.