Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391025 | 0.77 | — | — | |
| SCHEMBL8847359 | 0.77 | — | — | |
| Potassium Ion SCHEMBL18300804 | 0.76 | — | — | |
| Potassium Ion SCHEMBL18300803 | 0.76 | — | — | |
| SCHEMBL12011403 | 0.72 | — | — | |
| SCHEMBL8856832 | 0.65 | — | — | |
| Bicarbonate SCHEMBL10889857 | 0.63 | — | — | |
| Bicarbonate SCHEMBL27540146 | 0.63 | — | — | |
| Oxalic Acid SCHEMBL14694753 | 0.63 | CA4 (0.70) | — | |
| Bicarbonate SCHEMBL176182 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635404-B | MCT4 inhibitors for the treatment of disease | 威特瑞有限公司 | 2021-09-28 | — | — | CN | disclosed |