Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680698 | 0.84 | HPGD (0.46) | ALDH1A1SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL28672305 | 0.84 | HPGD (0.51) | ALDH1A1RAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL28658410 | 0.82 | RAB9A (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL28490022 | 0.78 | CYP3A4 (0.55) | ALDH1A1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL11672970 | 0.75 | HPGD (0.54) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL11576952 | 0.74 | RAB9A (0.40) | ALDH1A1RAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL7201516 | 0.74 | LMNA (0.48) | ALDH1A1RAB9ASMN1; SMN2HPGDLMNA | |
| Hydrochloric Acid SCHEMBL11843807 | 0.74 | HPGD (0.53) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL31006500 | 0.72 | NPC1 (0.48) | ALDH1A1RAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL25247000 | 0.72 | HPGD (0.57) | ALDH1A1RAB9ASMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | claimed |
| CN-113698407-B | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | disclosed |