Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672305 | 0.86 | HPGD (0.51) | HPGDALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL28653873 | 0.84 | ALDH1A1 (0.43) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28653900 | 0.78 | MEN1 (0.52) | HPGDL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL1828325 | 0.77 | CES2 (0.52) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL25247000 | 0.77 | HPGD (0.57) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11835494 | 0.76 | CES2 (0.50) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28658410 | 0.75 | RAB9A (0.53) | HPGDALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL11254594 | 0.74 | CES2 (0.52) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 | |
| Toluene SCHEMBL8166865 | 0.73 | HPGD (0.43) | HPGDCASP3SENP8SENP7SENP6 | |
| Hydrochloric Acid SCHEMBL11842637 | 0.73 | ALDH1A1 (0.46) | HPGDALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | claimed |
| CN-113698407-B | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | disclosed |