Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164220 | 0.84 | POLB (0.49) | HSD17B2HSD17B1HTTMTNR1AMTNR1B | |
| SCHEMBL28653873 | 0.82 | ALDH1A1 (0.43) | RAB9ANPC1HSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL28672305 | 0.81 | HPGD (0.51) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28103467 | 0.80 | HSD17B2 (0.55) | RAB9ANPC1HSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL4293536 | 0.76 | MTNR1A (0.50) | RAB9ANPC1HSD17B2HSD17B1MTNR1A | |
| Hydrochloric Acid SCHEMBL11847191 | 0.76 | PARP1 (0.55) | RAB9ANPC1HSD17B2HSD17B1KDM4E | |
| SCHEMBL11578362 | 0.76 | RAB9A (0.46) | RAB9ANPC1HSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL28680698 | 0.75 | HPGD (0.46) | ALDH1A1HTTHPGDMAPTSMN1; SMN2 | |
| SCHEMBL27931266 | 0.75 | MTNR1A (0.51) | HSD17B2HSD17B1MTNR1AMTNR1BPARP1 | |
| SCHEMBL1144595 | 0.74 | MTNR1A (0.50) | HSD17B2HSD17B1MTNR1AMTNR1BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | claimed |
| CN-113698407-B | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-113698407-A | Method for preparing indazole [3,2-b ] quinazolin-7 (5H) -one derivative based on Ullmann coupling reaction | 武汉科技大学 | 2021-11-26 | — | — | CN | disclosed |