Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022955 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL28659204 | 0.95 | GPR35 (0.48) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL30022568 | 0.95 | GPR35 (0.48) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL19934782 | 0.89 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL19929844 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL28654877 | 0.87 | ADORA3 (0.52) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL30081078 | 0.87 | ABCG2 (0.47) | KDM4EALDH1A1HPGDABCG2SLC22A2 | |
| SCHEMBL28873061 | 0.87 | ABCG2 (0.47) | KDM4EALDH1A1HPGDABCG2SLC22A2 | |
| SCHEMBL30022887 | 0.85 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDABCG2POLB | |
| SCHEMBL30023352 | 0.84 | RXRA (0.38) | KDM4EALDH1A1HPGDABCG2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |