Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.44 |
| ▸ | THRB | P10828 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083009 | 0.84 | THRB (0.40) | THRATHRB | |
| SCHEMBL28664588 | 0.83 | ALDH1A1 (0.48) | THRATHRB | |
| SCHEMBL28675510 | 0.76 | THRB (0.56) | THRATHRB | |
| SCHEMBL28650024 | 0.73 | MCL1 (0.36) | — | |
| SCHEMBL28656735 | 0.73 | THRB (0.55) | THRATHRB | |
| SCHEMBL7086230 | 0.71 | THRA (0.60) | THRATHRB | |
| SCHEMBL2044734 | 0.71 | THRA (0.71) | THRATHRB | |
| SCHEMBL29066180 | 0.70 | THRB (0.41) | THRATHRB | |
| SCHEMBL8893247 | 0.70 | THRB (0.57) | THRATHRB | |
| SCHEMBL29527525 | 0.69 | THRB (0.38) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698388-B | 6-oxo-1, 6-dihydropyridine derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113698388-A | 6-oxo-1, 6-dihydropyridine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2021-11-26 | — | — | CN | disclosed |