Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587841 | 0.86 | ADORA1 (0.38) | GPR119ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28696148 | 0.74 | NR1H2 (0.38) | NR1H2HDAC1HDAC6GPR119EED | |
| SCHEMBL28449477 | 0.70 | USP2 (0.36) | NR1H2GPR119ALDH1A1ESR2GRM5 | |
| SCHEMBL20690515 | 0.70 | ALDH1A1 (0.40) | NR1H2GPR119ALDH1A1ESR2LMNA | |
| SCHEMBL2980997 | 0.68 | ESR2 (0.43) | NR1H2GPR119ALDH1A1ESR2LMNA | |
| SCHEMBL17481737 | 0.68 | USP2 (0.41) | NR1H2GPR119ALDH1A1ESR2LMNA | |
| SCHEMBL28686795 | 0.68 | ESR2 (0.34) | NR1H2GPR119ESR2GRM5USP2 | |
| SCHEMBL29100795 | 0.68 | ESR2 (0.34) | NR1H2GPR119ESR2GRM5USP2 | |
| SCHEMBL31729924 | 0.67 | CA1 (0.42) | NR1H2HDAC1HDAC6ALDH1A1UCHL1 | |
| SCHEMBL17942084 | 0.65 | GPR119 (0.39) | NR1H2GPR119ALDH1A1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767101-A | Novel indole-2-carboxamides having anti-Hepatitis B Virus (HBV) activity | 艾库里斯有限及两合公司 | 2021-12-07 | — | — | CN | disclosed |