Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 known ✓ | P03956 | 1/20 | 0.50 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL9243729 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| Lithium Ion SCHEMBL28656990 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| Potassium Ion SCHEMBL28668574 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL9165326 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL6274955 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL1499866 | 0.95 | RAPGEF4 (0.54) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL11837095 | 0.89 | RAPGEF4 (0.48) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL646619 | 0.87 | RAPGEF4 (0.47) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL4541179 | 0.79 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL1694111 | 0.79 | RAPGEF4 (0.41) | RAPGEF4CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119074563-A | Dental curable composition containing ultraviolet absorber | 株式会社松风 | 2024-12-06 | — | — | CN | disclosed |
| CN-113402666-B | Dental photocurable composition excellent in color tone selectivity | 株式会社松风 | 2024-11-15 | — | — | CN | disclosed |
| CN-113402665-B | Dental photocurable composition comprising a highly soluble photoacid generator | 株式会社松风 | 2024-11-15 | — | — | CN | disclosed |
| CN-118946340-A | Curable composition for dentistry having excellent color tone adaptability | 可乐丽则武齿科株式会社 | 2024-11-12 | — | — | CN | disclosed |
| CN-118510478-A | Curable composition for dental use, and dental patch comprising base material and resin layer | 可乐丽则武齿科株式会社 | 2024-08-16 | — | — | CN | disclosed |
| CN-114828803-B | Dental restorative composition | 可乐丽则武齿科株式会社 | 2024-08-16 | — | — | CN | disclosed |
| CN-117597099-A | Curable composition for dental use | 可乐丽则武齿科株式会社 | 2024-02-23 | — | — | CN | disclosed |
| CN-113677293-B | Curable composition for dental restoration | 可乐丽则武齿科株式会社 | 2023-10-10 | — | — | CN | disclosed |
| CN-116367806-A | Curable composition for dentistry having excellent color tone adaptability | 可乐丽则武齿科株式会社 | 2023-06-30 | — | — | CN | disclosed |
| CN-113677293-A | Curable composition for dental repair | 可乐丽则武齿科株式会社 | 2021-11-19 | — | — | CN | disclosed |