Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL28656990 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| Potassium Ion SCHEMBL28668574 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1499866 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9165326 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28656336 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6274955 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| Silver SCHEMBL9243729 | 0.87 | RAPGEF4 (0.54) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL11837095 | 0.81 | RAPGEF4 (0.48) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1694111 | 0.76 | RAPGEF4 (0.41) | RAPGEF4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4541179 | 0.76 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015649-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9365543-B2 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE | 2016-06-14 | — | — | US | disclosed |
| US-20150353523-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-9056853-B2 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20140378458-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2014-12-25 | — | — | US | disclosed |
| US-8772289-B2 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20130079513-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2013-03-28 | — | — | US | disclosed |
| US-8338419-B2 | N-thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2012-12-25 | — | — | US | disclosed |
| US-20120149705-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2012-06-14 | — | — | US | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20080221168-A1 | Methyl-phenyl-sulfamoyl-N-(5-bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid (2-carbamoyl-6-methyl-phenyl))-amide | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221168-A1 | Methyl-phenyl-sulfamoyl-N-(5-bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid (2-carbamoyl-6-methyl-phenyl))-amide | AADAC, AAAS, ACMSD | RAPGEF4 3503/4885F2 182/4885PRSS1 1421/4885 |
| US-20120149705-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, NIT2 | RAPGEF4 2322/4885F2 202/4885PRSS1 2551/4885 |
| US-20140378458-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | RAPGEF4 2406/4885F2 446/4885PRSS1 2135/4885 |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | RAPGEF4 2982/4885F2 980/4885PRSS1 1362/4885 |
| US-20170015649-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | RAPGEF4 2406/4885F2 446/4885PRSS1 2135/4885 |
| US-20150353523-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | RAPGEF4 2406/4885F2 446/4885PRSS1 2135/4885 |
| US-20130079513-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | RAPGEF4 2406/4885F2 446/4885PRSS1 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.