Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28340679 | 0.84 | — | — | |
| Acetic Acid SCHEMBL27153896 | 0.82 | FFAR3 (0.58) | CA2CA1CA9THRBALDH1A1 | |
| Bicarbonate SCHEMBL28136957 | 0.80 | CA2 (0.50) | CA2CA1CA9THRBALDH1A1 | |
| Bicarbonate SCHEMBL28016701 | 0.79 | ALDH1A1 (0.44) | CA2CA1CA9THRBALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9228519 | 0.76 | CA2 (0.46) | CA2CA1CA9THRBALDH1A1 | |
| Acetone SCHEMBL27619352 | 0.76 | LMNA (0.55) | CA2CA1THRBALDH1A1TSHR | |
| Bicarbonate SCHEMBL28226829 | 0.76 | ALDH1A1 (0.47) | CA2CA1CA9THRBALDH1A1 | |
| Bicarbonate SCHEMBL28722588 | 0.76 | — | — | |
| Bicarbonate SCHEMBL31025874 | 0.73 | THRB (0.33) | CA2CA1CA9THRBALDH1A1 | |
| Bicarbonate SCHEMBL21051129 | 0.73 | CA2 (0.42) | CA2CA1CA9THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109314269-B | Lithium ion battery and preparation method thereof | 罗伯特·博世有限公司 | 2021-10-29 | — | — | CN | claimed |