Sugi Predict

Sugi Predict / Compounds / SCHEMBL28658

SCHEMBL28658

SCHEMBL28658

C1CC2(CCN1)CCNCC2

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.42
▸ USP2 O75604 3/20 0.42
▸ HIF1A Q16665 2/20 0.42
▸ MAPT P10636 1/20 0.42
▸ PDE4A P27815 1/20 0.42
▸ KDR P35968 1/20 0.42
▸ TSHR P16473 4/20 0.41
▸ CYP3A4 P08684 2/20 0.41
▸ CYP2C9 P11712 3/20 0.38
▸ CYP2C19 P33261 3/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ HPGD P15428 3/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ MAPK1 P28482 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346839 0.96 — —
Hydrochloric Acid SCHEMBL29784260 0.96 CYP2D6 (0.41) CYP2D6USP2HIF1AMAPTPDE4A
SCHEMBL11351132 0.96 CYP2D6 (0.41) CYP2D6USP2HIF1AMAPTPDE4A
SCHEMBL20160644 0.96 CYP2D6 (0.41) CYP2D6USP2HIF1AMAPTPDE4A
Hydrochloric Acid SCHEMBL2855605 0.92 — —
SCHEMBL30637307 0.92 — —
Bromide SCHEMBL2686491 0.92 — —
SCHEMBL18211911 0.89 CYP2D6 (0.38) CYP2D6USP2HIF1AMAPTPDE4A
SCHEMBL1797025 0.89 — —
SCHEMBL28081 0.89 CYP2D6 (0.38) CYP2D6USP2TSHRCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF GENOSCO INC (US) 2026-04-23 — — US claimed
EP-4695256-A2 ERBB2 INHIBITORS Cogent Biosciences, Inc. (US) 2026-02-18 — — EP claimed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 — — EP claimed
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF VORONOI, INC. (KR) 2025-12-04 — — US claimed
US-20250263412-A1 NON-HYDROXAMATE HDAC6 INHIBITORS AND RELATED METHODS OF USE THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 — — US claimed
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 — — US claimed
EP-4559920-A1 MACROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2025-05-28 — — EP claimed
US-20250129078-A1 ERBB2 INHIBITORS COGENT BIOSCIENCES, INC. 2025-04-24 — — US claimed
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
CN-119661529-A Synthesis method of 3, 9-diazaspiro [5.5] undecane-3-tert-butyl formate 上海馨远医药科技有限公司 2025-03-21 — — CN claimed
US-20140142084-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) 2014-05-22 — — US claimed
US-8680092-B2 Nitrogenous heterocyclic compound and medicinal use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2014-03-25 — — US claimed
US-8618111-B2 5-alkynyl-pyrimidines BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-12-31 — — US claimed
EP-2528910-A1 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS Boehringer Ingelheim International GmbH (DE) 2012-12-05 — — EP claimed
EP-2414330-A2 PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS Merck Patent GmbH (DE) 2012-02-08 — — EP claimed
US-20120028958-A1 5-ALKYNYL-PYRIMIDINES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-02-02 — — US claimed
WO-2011092197-A1 5-ALKYNYL PYRIMIDINES AND THEIR USE AS KINASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-04 — — WO claimed
WO-2010115491-A2 PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS MERCK PATENT GMBH (DE) 2010-10-14 — — WO claimed
EP-1926730-A1 NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES AstraZeneca AB (SE) 2008-06-04 — — EP claimed
WO-2007030061-A1 NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES ASTRAZENECA AB (SE) 2007-03-15 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120028958-A1 5-ALKYNYL-PYRIMIDINES MKI67, CCNA1, CCNT1 CYP2D6 298/4885USP2 4490/4885HIF1A 503/4885
US-20140142084-A1 NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND FGFR3, FGFR1, FGFR2 CYP2D6 3351/4885USP2 3284/4885HIF1A 787/4885
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF CRBN, PSMB3, PSMB1 CYP2D6 3102/4885USP2 117/4885HIF1A 1493/4885
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF ERBB2, EGFR, ERBB3 CYP2D6 2116/4885USP2 2937/4885HIF1A 678/4885
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL CYP2D6 727/4885USP2 1903/4885HIF1A 3704/4885
US-20250129078-A1 ERBB2 INHIBITORS ERBB2, ERBB3, EGFR CYP2D6 1436/4885USP2 3238/4885HIF1A 2509/4885
US-20250263412-A1 NON-HYDROXAMATE HDAC6 INHIBITORS AND RELATED METHODS OF USE HDAC6, HHAT, HDAC1 CYP2D6 3822/4885USP2 2259/4885HIF1A 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.