Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.58 |
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350811 | 1.00 | HRH1 (0.58) | HRH1SETD7HTR2CHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9333806 | 0.98 | LMNA (0.59) | HRH1SETD7HTR2CHTTALDH1A1 | |
| Bromide SCHEMBL11621168 | 0.98 | HRH1 (0.56) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL11736306 | 0.87 | HRH1 (0.46) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL10409036 | 0.86 | HRH1 (0.45) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL3036664 | 0.84 | HRH1 (0.49) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL14825794 | 0.82 | HRH1 (0.49) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL3046164 | 0.82 | HRH1 (0.50) | HRH1SETD7HTR2CHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9631090 | 0.81 | SETD7 (0.50) | HRH1SETD7HTR2CHTTALDH1A1 | |
| SCHEMBL11883313 | 0.79 | SETD7 (0.61) | HRH1SETD7HTR2CHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3047168-A | — | — | None | — | — | JP | disclosed |
| JP-5255249-A | — | — | None | — | — | JP | disclosed |
| JP-11246526-A | — | — | None | — | — | JP | disclosed |
| EP-4340940-A1 | COMPOSITIONS AND METHODS OF TISSUE REGENERATION THERAPY | The Regents of University of California (US) | 2024-03-27 | — | — | EP | disclosed |
| US-20230133974-A1 | HYBRIDOMA CELL LINE OF SECRETING CYPROHEPTADINE MONOCLONAL ANTIBODIES AND PREPARATION METHOD THEREOF | JIANGNAN UNIVERSITY (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230133974-A1 | HYBRIDOMA CELL LINE OF SECRETING CYPROHEPTADINE MONOCLONAL ANTIBODIES AND PREPARATION METHOD THEREOF | JIANGNAN UNIVERSITY (CN) | 2023-05-04 | — | — | US | disclosed |
| US-10568851-B2 | Compounds and methods of treating ocular disorders | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-10426773-B2 | Systems pharmacology for treating ocular disorders | CASE WESTERN UNIVERSITY (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190284303-A1 | Hybridoma cell line of secreting cyproheptadine monoclonal antibodies and preparation method thereof | JIANGNAN UNIVERSITY | 2019-09-19 | — | — | US | disclosed |
| US-20190099420-A1 | SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS | CASE WESTERN UNIVERSITY | 2019-04-04 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| US-5095022-A | Antiallergens | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| JP-H0347168-A | PIPERIDINE DERIVATIVE AND HYPOTENSOR CONTAINING SAME DERIVATIVE | AJINOMOTO CO INC | 1991-02-28 | — | — | JP | disclosed |
| EP-0406739-A2 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4912222-A | Antihistamines related to cyproheptadine | FISONS CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| WO-1989012443-A1 | NOVEL DIBENZO-CYCLOHEPTENYL, -CYCLOHEPTYL AND -OXEPINYL AMINES HAVING ANTIHISTAMINIC PROPERTIES | FISONS CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |
| EP-0347123-A2 | Dibenzo-cycloheptenyl, -cycloheptyl and -oxepinyl amines having antihistaminic properties | FISONS CORPORATION (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4089864-A | 4-(10,11-Dihydro-cis and trans-10,11-dihydroxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidines | MERCK & CO., INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426773-B2 | Systems pharmacology for treating ocular disorders | GRK1, MTNR1A, MTNR1B | HRH1 316/4885SETD7 4871/4885HTR2C 291/4885 |
| US-20230133974-A1 | HYBRIDOMA CELL LINE OF SECRETING CYPROHEPTADINE MONOCLONAL ANTIBODIES AND PREPARATION METHOD THEREOF | HRH1, HRH2, HRH3 | HRH1 1/4885SETD7 3560/4885HTR2C 215/4885 |
| US-20190099420-A1 | SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS | GRK1, MTNR1A, MTNR1B | HRH1 316/4885SETD7 4871/4885HTR2C 291/4885 |
| US-10568851-B2 | Compounds and methods of treating ocular disorders | ALDH1A2, TXNRD2, TXNRD1 | HRH1 1335/4885SETD7 4851/4885HTR2C 3728/4885 |
| US-20190284303-A1 | Hybridoma cell line of secreting cyproheptadine monoclonal antibodies and preparation method thereof | HRH1, HRH2, HRH3 | HRH1 1/4885SETD7 3560/4885HTR2C 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.