Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | PKM | P14618 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668702 | 0.84 | CTH (0.47) | CTHKMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL28524097 | 0.80 | CTH (0.50) | CTHKMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL28643368 | 0.76 | RAB9A (0.58) | CTHKMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL28663162 | 0.71 | CTH (0.45) | CTHKMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL28648148 | 0.68 | CTH (0.53) | CTHKMT2AHTTNPC1RAB9A | |
| SCHEMBL30211824 | 0.67 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2KDM4EHTTMAPT | |
| SCHEMBL9735520 | 0.65 | RAB9A (0.58) | KMT2ASMN1; SMN2KDM4EHTTMAPT | |
| SCHEMBL2800046 | 0.64 | KDM4E (0.60) | KMT2ASMN1; SMN2KDM4EHTTMAPT | |
| SCHEMBL13201844 | 0.64 | KDM4E (0.60) | KMT2ASMN1; SMN2KDM4EHTTMAPT | |
| SCHEMBL22342567 | 0.64 | CTH (0.51) | CTHKDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400625-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |