Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631623 | 0.82 | PAX8 (0.65) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL8342118 | 0.82 | PAX8 (0.65) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL5051613 | 0.82 | PAX8 (0.65) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL28643368 | 0.82 | RAB9A (0.58) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL6714490 | 0.82 | RAB9A (0.55) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL6714484 | 0.82 | RAB9A (0.55) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL28952987 | 0.80 | PAX8 (0.70) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL4927052 | 0.77 | PAX8 (0.70) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL30587491 | 0.75 | SMN1; SMN2 (0.60) | RAB9ANPC1GAASMN1; SMN2LMNA | |
| SCHEMBL12720910 | 0.74 | RAB9A (0.58) | RAB9ANPC1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084458-A | Bactericides, malaria and antitumor agents | SCHAPER KLAUS JUERGEN (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4997835-A | Bactericides, malaria, antitumor | SCHAPER KLAUS JUERGEN (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0313630-A1 | SUBSTITUTED 2-ACYLPYRIDIN-ALPHA-(N)-HETARYLHYDRAZONES AND MEDICAMENTS CONTAINING SAME. | DEUTSCHES AUSSATZIGEN HILFSWER (DE) | 1989-05-03 | — | — | EP | disclosed |