Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670379 | 0.86 | ADORA3 (0.56) | TNKSALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL19929823 | 0.84 | ADORA3 (0.54) | TNKSALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28929133 | 0.82 | MAOB (0.48) | TNKSALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL28655613 | 0.82 | MAOB (0.50) | TNKSRAB9ANPC1MEN1KMT2A | |
| SCHEMBL28663810 | 0.80 | ALDH1A1 (0.64) | ALDH1A1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL28654878 | 0.78 | CA12 (0.49) | TNKSALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28677812 | 0.77 | CA12 (0.42) | ALDH1A1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL30020913 | 0.76 | MAPT (0.48) | TNKSALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28660357 | 0.76 | EIF4A1 (0.52) | — | |
| SCHEMBL28655615 | 0.75 | DHODH (0.53) | ALDH1A1RAB9AKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |