Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | EPRS1 | P07814 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655613 | 0.86 | MAOB (0.50) | MAOBNPC1RAB9ATNKSGABRP | |
| SCHEMBL28670379 | 0.85 | ADORA3 (0.56) | MAOBNPC1RAB9ATNKSRXFP1 | |
| SCHEMBL28660360 | 0.82 | TNKS (0.54) | MAOBNPC1RAB9ATNKSKDM4E | |
| SCHEMBL28660357 | 0.80 | EIF4A1 (0.52) | EIF4A1 | |
| SCHEMBL28663810 | 0.79 | ALDH1A1 (0.64) | NPC1RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL28655615 | 0.77 | DHODH (0.53) | MAOBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28654878 | 0.77 | CA12 (0.49) | MAOBNPC1RAB9ATNKSKDM4E | |
| SCHEMBL28677812 | 0.76 | CA12 (0.42) | MAOBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19929823 | 0.75 | ADORA3 (0.54) | MAOBNPC1RAB9ATNKSRXFP1 | |
| SCHEMBL27557477 | 0.74 | RXFP1 (0.50) | NPC1EPRS1RXFP1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113754619-A | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2021-12-07 | — | — | CN | disclosed |