Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022887 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28668413 | 0.83 | MEN1 (0.47) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30022975 | 0.83 | PTGS2 (0.41) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30023487 | 0.83 | DHODH (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL30022919 | 0.81 | PTPN22 (0.50) | — | |
| SCHEMBL30023283 | 0.81 | KDM4E (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28677868 | 0.81 | KDM4E (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30023247 | 0.81 | KDM4E (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28680766 | 0.81 | KDM4E (0.45) | MAPTALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30023062 | 0.80 | MAPT (0.46) | MAPTALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |