Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923445 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1704181 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL30005976 | 0.76 | RXFP1 (0.50) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL375020 | 0.76 | RXFP1 (0.50) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL20560249 | 0.76 | ALOX15 (0.43) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL29716064 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL21585803 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL24868777 | 0.72 | BTK (0.40) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28355716 | 0.72 | KMT2A (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1282557 | 0.72 | PDK1 (0.45) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404497-B | Preparation method of polysubstituted bromofluorine substituted benzimidazole compound | 北京六合宁远科技有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-110404497-B | Preparation method of polysubstituted bromofluorine substituted benzimidazole compound | 北京六合宁远科技有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-110404497-B | Preparation method of polysubstituted bromofluorine substituted benzimidazole compound | 北京六合宁远科技有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-110404497-A | Preparation method of polysubstituted bromofluorine substituted benzimidazole compound | BEIJING LIUHE NINGYUAN TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |