Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362269 | 0.77 | PIK3CA (0.30) | — | |
| SCHEMBL28669003 | 0.74 | HRH3 (0.34) | CDK2FLT3CCNA1ROCK2SMN1; SMN2 | |
| SCHEMBL19362425 | 0.71 | — | — | |
| SCHEMBL19360214 | 0.71 | JUN (0.34) | ALDH1A1KDM4E | |
| SCHEMBL23999684 | 0.69 | ALDH1A1 (0.39) | CDK2FLT3CCNA1ROCK2ALDH1A1 | |
| SCHEMBL19349909 | 0.67 | JUN (0.35) | — | |
| SCHEMBL25821294 | 0.66 | KMT2A (0.33) | ROCK2ALDH1A1KDM4E | |
| SCHEMBL16168690 | 0.66 | DPP4 (0.40) | ROCK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2713361 | 0.66 | LMNA (0.45) | HTR7ROCK2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13533343 | 0.66 | HTR7 (0.70) | HTR7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727758-A | Bicyclic heterocyclic compounds and use thereof | 锐新医药公司 | 2021-11-30 | — | — | CN | disclosed |