Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053177 | 0.82 | GRM1 (0.53) | NAMPTGRM1GRM5 | |
| SCHEMBL28672701 | 0.77 | JMJD6 (0.41) | TP53QDPRGRM1GRM5SHMT2 | |
| SCHEMBL18865732 | 0.76 | ALDH1A1 (0.39) | NAMPTQDPRGRM1GRM5SMN1; SMN2 | |
| SCHEMBL15025632 | 0.76 | CCR1 (0.49) | NAMPTQDPRGRM1GRM5SMN1; SMN2 | |
| SCHEMBL16992268 | 0.73 | ALDH1A1 (0.39) | NAMPTTP53QDPRGRM1GRM5 | |
| SCHEMBL30711189 | 0.72 | RAB9A (0.44) | GRM1GRM5SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20140095 | 0.72 | HTR1A (0.54) | GRM1GRM5SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28791729 | 0.71 | QDPR (0.42) | NAMPTTP53QDPRSHMT2SMN1; SMN2 | |
| SCHEMBL3256667 | 0.70 | SMN1; SMN2 (0.42) | NAMPTTP53QDPRSMN1; SMN2ALDH1A1 | |
| SCHEMBL16423118 | 0.70 | GRM1 (0.39) | NAMPTQDPRGRM1GRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735825-A | 1,2,3, 6-tetrahydropyridine compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2021-12-03 | — | — | CN | disclosed |