Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL41 | 0.94 | — | — | |
| Potassium Ion SCHEMBL14630574 | 0.94 | TSHR (0.30) | — | |
| Potassium Ion SCHEMBL4441965 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL545541 | 0.88 | — | — | |
| Potassium Ion SCHEMBL3178692 | 0.88 | — | — | |
| Potassium Ion SCHEMBL9325821 | 0.88 | — | — | |
| Potassium Ion SCHEMBL21360011 | 0.88 | — | — | |
| Water SCHEMBL182730 | 0.88 | — | — | |
| SCHEMBL22800862 | 0.88 | — | — | |
| Potassium Ion SCHEMBL8645894 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510332-A | New method for synthesizing 6, 8-dichloro octanoic acid ester | 风火轮(上海)生物科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-116903500-A | Method for synthesizing p-methylsulfonyl benzaldehyde | 上海颐碳化学科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116396205-A | N-aryl indole derivative and preparation method and application thereof | 沈阳药科大学 | 2023-07-07 | — | — | CN | claimed |
| CN-115650983-A | Synthesis method of entecavir intermediate N4 | 南京康立瑞生物科技有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115010623-A | Preparation method of 2-cyanoethyl diethyl malonate | 福建科宏生物工程股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| WO-2022101939-A1 | NOVEL PROCESS FOR THE PREPARATION OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE OR ITS SALTS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2022-05-19 | — | — | WO | claimed |
| EP-3041832-A1 | STEREOSELECTIVE SYNTHESIS OF DIOLS AND TRIOLS BY MANNICH REACTION AND THEIR USE IN THE SYNTHESIS OF CARFILZOMIB | Sandoz AG (CH) | 2016-07-13 | — | — | EP | claimed |
| US-20160194354-A1 | STEREOSELECTIVE SYNTHESIS OF DIOLS AND TRIOLS BY MANNICH REACTION AND THEIR USE IN THE SYNTHESIS OF CARFILZOMIB | SANDOZ GMBH (AT) | 2016-07-07 | — | — | US | claimed |
| WO-2015162506-A1 | PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND NOVEL INTERMEDIATES | SUVEN LIFE SCIENCES LIMITED (IN) | 2015-10-29 | — | — | WO | claimed |
| WO-2015032622-A1 | STEREOSELECTIVE SYNTHESIS OF DIOLS AND TRIOLS BY MANNICH REACTION AND THEIR USE IN THE SYNTHESIS OF CARFILZOMIB | SANDOZ AG (CH) | 2015-03-12 | — | — | WO | claimed |
| EP-2168969-A2 | Racemization and Enantiomer Separation of Clopidogrel | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-03-31 | — | — | EP | claimed |
| EP-1483269-B1 | RACEMIZATION AND ENANTIOMER SEPARATION OF CLOPIDOGREL | TEVA PHARMA (IL) | 2009-10-14 | — | — | EP | claimed |
| EP-1483269-A1 | RACEMIZATION AND ENANTIOMER SEPARATION OF CLOPIDOGREL | Teva Pharmaceutical Industries Limited (IL) | 2004-12-08 | — | — | EP | claimed |
| WO-2004013147-A1 | RACEMIZATION AND ENANTIOMER SEPARATION OF CLOPIDOGREL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-02-12 | — | — | WO | claimed |
| CN-117510332-A | New method for synthesizing 6, 8-dichloro octanoic acid ester | 风火轮(上海)生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-116903500-A | Method for synthesizing p-methylsulfonyl benzaldehyde | 上海颐碳化学科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116396205-A | N-aryl indole derivative and preparation method and application thereof | 沈阳药科大学 | 2023-07-07 | — | — | CN | disclosed |
| WO-2004013147-A1 | RACEMIZATION AND ENANTIOMER SEPARATION OF CLOPIDOGREL | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-02-12 | — | — | WO | disclosed |
| US-20040024012-A1 | Racemization and enantiomer separation of clopidogrel | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-02-05 | — | — | US | disclosed |
| US-20040024011-A1 | RACEMIZATION AND ENANTIOMER SEPARATION OF CLOPIDOGREL | TEVA PHARMACEUTICALS USA, INC. | 2004-02-05 | — | — | US | disclosed |