Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836900 | 0.86 | ALDH1A1 (0.34) | SSTR4KDM4EMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2835500 | 0.85 | ALDH1A1 (0.33) | SSTR4KDM4EMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2840884 | 0.85 | SCD (0.37) | SSTR4SSTR1 | |
| Hydrochloric Acid SCHEMBL2844001 | 0.81 | NPSR1 (0.31) | ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL3579452 | 0.80 | SSTR4 (0.40) | SSTR4KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2842783 | 0.80 | SSTR1 (0.31) | SSTR4SSTR1 | |
| Hydrochloric Acid SCHEMBL2837962 | 0.79 | SSTR1 (0.30) | SSTR4SSTR1 | |
| Hydrochloric Acid SCHEMBL2841114 | 0.79 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2844254 | 0.78 | SLC6A2 (0.36) | SSTR4CHRM3 | |
| SCHEMBL2882304 | 0.78 | HTR2A (0.40) | KDM4EMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20100048537-A1 | HETEROARYL DERIVATIVES | NIPPON SHINYAKU CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2141168-A1 | HETEROARYL DERIVATIVES | Nippon Shinyaku Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048537-A1 | HETEROARYL DERIVATIVES | OPRD1, OPRM1, OPRK1 | SSTR4 1737/4885RBP4 4539/4885TTR 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.